Saturday, February 22, 2025

Genetic engineering and computing, with nanotechnology, have a brilliant future.


"Researchers at the University of Galway have created APOLLO, the world’s largest collection of digital microbe models—247,092 in total—to revolutionize our understanding of the human microbiome and its role in health. This unprecedented database will enable scientists to study how microbes interact with the body, accelerating discoveries in diagnostics, treatments, and precision healthcare. Credit: University of Galway" (ScitechDaily, Meet APOLLO: Researchers Create World’s Largest Digital Microbe Collection)

The next-generation nanotechnology. Genetic engineering is an interesting, promising, and frightening tool. Genetic engineering means that researchers can manipulate the cell's genomes. They can transform one cell into another one. They can create multiple copies of the cells. And the highly advanced nanotechnology makes it possible to create DNA by using digitally stored information. 

If the genetic data is stored in the digital archives. Like a computer's hard disk that makes deadly viruses safer. The highly advanced simulations are tools that allow us to test chemicals and their influence on cells and viruses that can be dangerous. The knowledge of the information that the DNA involves and the points where certain data is stored helps to create simulations or digital twins for the viruses and bacteria. Those things can make it possible to create things like sonic waves that can destroy only infected cells.  


"A study reveals that the fungus Beauveria bassiana manipulates fruit flies’ immune systems to kill brain cells, causing neurodegeneration, highlighting how fungal infections could, in principle, affect the human brain." (ScitechDaily, This Deadly Fungus “Hacks” the Immune System, Causing the Brain To Self-Destruct)

The ability to hack the immune system makes it possible to create medicals that will not activate the immune system. Same way organ transplants can survive better if the tissue itself orders the immune cells to stay off that tissue. That makes it possible to remove the immune suppression medicines. But those technologies are under research. The ability to create tissue or organs that can suppress the immune system only on that tissue or organ could be a breakthrough. 

The deadly parasite fungus is the thing that can reorder the cells to die. That effect is seen in the banana flies. There is the possibility to create genetically engineered fungus that travels to the cancer cells. Then the fungus can destroy the targeted cells. This kind of fungus can also make many other medicines unnecessary, but the problem is that those funguses can also offer the worst biological weapons that we can imagine. 

That fungus can cause gangrenes. Also in the human body.  But if the researchers can manipulate that fungus. It infects only the cancer or bacteria tissues that can make new types of medical treatment possible. In some scenarios, the worms can be manipulated to make the clones of the human cells. And those cells can be used to fix tissue damage. 

But there is an interesting scenario about devices that can regenerate the body. Is quite easy to create the DNA bite that can cause cells to divide. The problem is that the DNA in the cells must be renewed. That thing is easy to make for individual cells. But the problem is that there are lots of cells in the human body. The system must remove and replace the DNA from the cell's nucleus. Then it must replace the old mitochondria using fresh ones. 

If that kind of thing is possible for a large number of cells, there is the possibility that the fresh cells order the old ones to die. The genetically engineered fungus can make that thing possible. The problem in tissue renewal and fixing damages in the body include similar problems. There must be cells or nutrients for fast-dividing cells. 

The genetically engineered fungus can spray those cells into the right positions in the body. The fungus can involve genetic detectors that make it possible to create different types of cells. The problem is how to make enough cells that can fit precisely in the right places in the body. If that thing is possible that kind of technology will allow to creation of systems that can fix even large damages to the human body. And the same systems can increase our lifetime. 


 https://bigthink.com/health/the-quest-for-a-communication-device-that-tells-cells-to-regenerate-the-body/


 https://scitechdaily.com/meet-apollo-researchers-create-worlds-largest-digital-microbe-collection/


 https://scitechdaily.com/this-deadly-fungus-hacks-the-immune-system-causing-the-brain-to-self-destruct/

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Genetic engineering and computing, with nanotechnology, have a brilliant future.

"Researchers at the University of Galway have created APOLLO, the world’s largest collection of digital microbe models—247,092 in total...