Showing posts with label medicines. Show all posts
Showing posts with label medicines. Show all posts

Tuesday, January 21, 2025

The new medicine activates the death receptor (DR5) on the cancer cells.


"Scientists engineered tiny vesicles to target cancer cells via DR5, showing strong tumor-killing effects in lab and animal studies. This therapy may offer an easily manufactured, off-the-shelf option for solid tumor treatment." (ScitechDaily, 20 Years in the Making: Scientists Unveil Breakthrough Anticancer Weapon)

The new medical treatment or medicine is based on capsules. That is made of human cell proteins. The idea is that when the dead cell is brought near or in the cell group that thing can cause gangrene. Dead cells can kill other cells. The problem is how to inject those particles into the cancer cells. Those cell particles activate the receptor that researchers call a "self-destruction receptor". 

"A new twist on a decades-old anticancer strategy has demonstrated significant potential against various cancer types in a preclinical study conducted by researchers at the Perelman School of Medicine at the University of Pennsylvania. The innovative method employs small extracellular vesicles (sEVs)—tiny capsules engineered from human cells—offering a promising new avenue for immunotherapy. This approach is now advancing toward further development and testing." (ScitechDaily, 20 Years in the Making: Scientists Unveil Breakthrough Anticancer Weapon)


The researchers noticed that protein activates the DR5 (death receptor 5) on the surface of cancer cells. Similar proteins activate similar receptors in the other cells. That thing makes gangrene so dangerous. There is the possibility that the nanocapsules that are made of the separated tumor cells and then injected back into the tumor will activate the DR5 receptor. The dead cell protein normally activates the DR5 receptors, but the strings that the cancer cell grows deny that the dead cells cannot touch those DR5 receptor proteins. 

The death receptor activator is effective against many cancer types. That is the new path for immune therapy. There is also planned to use the DNA that nanoparticles transport to destroy cancer cells. The nanoparticle transports artificial DNA that orders cells to die into cancer cells. However, the problem is that the researchers must get those DNA bites to the right cells. 

Researchers used 20 years to make the perfect medicine against cancer. This new medicine is the nanoparticle that transports the death code to the cancer cells. Theoretically, this kind of thing is very easy to make. The end of the DNA involves the genetic code that kills cancer cells. That means those DNA bites simply order those cells to die. 

But the practical problems are big. The nanoparticles must go to the right cells or they can cause devastating effects. If the "killer DNA" goes into the healthy tissues, that can cause gangrene. Researchers must make a nanoparticle that holds nutrients that only cancer cells use. And if they find that nutrient this technology is a holy grail for medical factories. 


https://scitechdaily.com/20-years-in-the-making-scientists-unveil-breakthrough-anticancer-weapon/


Sunday, December 22, 2024

Scientists crack cell communication.


"Mirror life presents serious dangers, primarily due to its potential to interact unpredictably with the natural world. Without natural checks like predators or antibiotics, mirror organisms could replicate uncontrollably, creating risks that scientists are only beginning to understand. Credit: SciTechDaily.com" (ScitechDaily, “Mirror Bacteria” Warning: A New Kind of Life Could Pose a Global Threat)

 Scientists crack cell communication. Or, they crack the chemical messages. That the cells use to communicate with each other. Along with new observation tools. That makes the system able to communicate with bacteria and immune cells. The reality is this. If something needs to be controlled by some system. That requires that the controller can observe the system. 

The new systems are tools that can turn the bacteria into miniature biorobots. It's possible. The manipulated bacteria can be from those communication chemicals. 

The other way to turn bacteria into robots is to put microchips in them. Nanotechnology makes it possible to create small systems that can turn the bacteria's DNA plasmids. The DNA plasmid is the ring-shaped DNA in the bacteria. And that is the chemical brain of those tiny organisms. 


If the system can read DNA that turns bacteria into zombies that makes what the controller wants. Turning the DNA plasmid into the right position makes it possible to turn bacteria into the zombie that attacks against other bacteria. The ability to read the bacteria's communication. Allows the system to order bacteria to attack against wanted cells and chemicals. And in the ideal situation, the system just orders bacteria to leave the body. 

Mirror bacteria are like natural bacteria's evil twins. They produce proteins and enzymes that act the wrong way. Or they can inject the genome into the targeted cells that act the wrong way. The idea would be that the mirror bacteria can inject the mirror genome into the cancer cells. The ability to read genetic code makes new types of medicals and vaccines possible, 


The thing is that bioengineering and genetic engineering make it possible to create so-called mirror bacteria. Those bacteria are the natural bacteria's evil twins that can cause problems if they are released into nature. Those evil twin bacteria developed in medical research. Their mission is to develop the proteins that go into the targeted bacteria. In the wrong ways. Or if those bacteria will exchange genomes to other bacteria they pump their DNA into the receiver the wrong way. 

And that should cause death for those targeted bacteria. But those mirror bacteria can cause very bad problems or disasters in nature. The idea in the mirror bacteria is that they are like some kind of "Nosferatu" or vampire bacteria. Just like "Nosferatu's" evil Count Orlok or some Count Dracula are the human's evil twins those mirror bacteria are also evil twins of bacteria.  The function of the mirror bacteria is. Its genomes act backward to their natural companion bacteria. And that makes them very dangerous tools in the wrong hands. 



https://scitechdaily.com/mirror-bacteria-warning-a-new-kind-of-life-could-pose-a-global-threat/


https://scitechdaily.com/scientists-have-finally-cracked-the-code-of-cellular-communication/  


 https://scitechdaily.com/unlocking-the-genetic-code-to-supercharge-flu-vaccines/  


Astronomers could have a model for why photons from GRB 221009A were at a high energy level.

"An illustration shows a photon from the biggest cosmic explosion since the Big Bang reaching Earth. (Image credit: Robert Lea (created...