Showing posts with label Aging. Show all posts
Showing posts with label Aging. Show all posts

Monday, June 9, 2025

How to slow aging?



"Illustration of a healthy cell (left) alongside a cell that has been affected by necrosis (right). Credit: LinkGevity" (ScitechDaily, “Pausing” Cell Death Could Be the Key to Longevity)


Pausing the programmed cell death can improve our lifetime. But there is one problem with that. The purpose of programmed cell death is to remove old cells from our body. Things like chemical stress from the environment and cell metabolism cause damage to the cell nucleus and mitochondrial DNA. So if we want to make ourselves “immortal” using a method where the programmed cell death is “paused” that can cause other diseases like cancer. So, if we want to make us live longer that means we should live like vampires. We should avoid sunlight and many other things. 

And that makes pausing the programming cell death alone not as good an idea as we might want to believe. There must be something that renews the DNA in the nucleus and mitochondria that will be useful for making us live longer, more qualified lives. The programmed cell death can also make it more effective to make the cells mark themselves and their proteins to things that the immune- and lymphatic system transports out from the body immediately. 

The main problem with cell death is this: When a cell dies or destroys itself it leaves proteins and poisonous metabolism production behind it. Those things cause problems with other cells. If the cell destroys itself by using some acids Those acids can damage other cells. So it would be safer that the cell that should die calls the immune cell that closes it in the slime before that process starts. That denies those acids and poisons interact with other cells. Another thing that can make cells more effective is that they can create the slime ball that closes the metabolism waste inside it. 



"Scientists have finally answered how ATP, the energy currency of the cell, is transported into the endoplasmic reticulum. Credit: Shutterstock" (ScitechDaily, Scientists Solve Decades-Old Cell Biology Mystery)

Those slime balls are safer to transport out of the body. So the cell must act with those cabbages like immune cells act with viruses. Those slime lumps can close those cabbages or metabolism waste inside them, and that decreases those poisonous compounds affecting other cells. Also it would be safer to destroy things like viruses and bacteria in the slime cells. That denies those antigens and bacteria metabolism wastes to spread to the body. And that is one of the things that can keep our cells in good condition. 

The best way would be for the slime cell to just close the dead cell in it and then cut it into pieces in the cell. That denies antibodies spread into the body. And that helps to keep our cells protected against those poisons. If we want to keep our cells qualified and able to operate we should also remove things like microplastics and other chemicals that stress our body. If those microplastics will start to spread into cells they might disturb things like cell organelles. Also, micro-particles can cause blockages in the small blood vessels. Same way microplastics can disturb mitochondria if they go into that cell organelle. 

The ability to change the DNA in the cell's nucleus and mitochondria can be possible quite soon. Researchers have found the key to the ATP synthesis that is the key element in a cell's mitochondrial energy production. There is a possibility that the biotechnical systems can give the antigen to that transplant DNA that makes the cell to drive it into the right cell organelle. This helps to replace the mitochondrial DNA as well as the DNA in the cell’s nucleus. If mitochondria can deny its metabolism, waste interaction with other cell structures that keeps cells cleaner. 


https://scitechdaily.com/pausing-cell-death-could-be-the-key-to-longevity/


https://scitechdaily.com/scientists-solve-decades-old-cell-biology-mystery/




Friday, February 14, 2025

Aging is an interesting thing.



"Selenoproteins play a crucial role in protecting blood-forming stem cells from oxidative damage. A study in Blood found that disrupting selenoprotein production impairs immune cell development and accelerates aging-related changes. However, dietary Vitamin E may help restore these functions, offering potential strategies to combat age-related diseases." (ScitechDaily, The Secret to Healthy Aging? Scientists Uncover the Power of Selenoproteins)


Theoretically making immortal creatures is quite an easy thing. The system must simply change the DNA in the mitochondria and the cell's nucleus. The system can store DNA in the digital form. And then nanotechnology restores that damaged DNA to its original form. The system removes damaged DNA from mitochondria and the cell's nucleus. And then it injects that fresh DNA into them. The problem is this: there are very many cells in the human body.  

Aging is one of the things. That is under research. The question about aging is mortality built in our DNA.  Or, does mortality come because of the outside effects? The outside effects. Metabolism production, Radiation, and toxins cause damage to the DNA. There is programmed cell death in the DNA. But sometimes that thing doesn't work. That makes the damaged cells make the descendants. 

Those damages cause mutations in the descendant cells and mitochondria. The mitochondria are the power sources for the cells. And those things have their own DNA and their own decay process. The question is which ages or dies first the cell's nucleus or mitochondria. 


Mitochondria take their own chemical signal to decay when the cell begins its mitosis. Researchers have noticed that selenoproteins can resist aging. That thing means that those proteins have some kind of effect on the cell's nucleus. Or maybe those proteins can affect mitochondria and their division. The protein can also slow aging by removing the products that mitochondria produce in metabolism. 

The mice that have human genomes help to solve what is the outside effect's role. And what is encoded in human DNA? Things like the aging process are important when people make long-term space travel to Mars and beyond. Things like cosmic radiation can destroy the DNA from cells and mitochondria. And that can accelerate aging. The cell's nucleus DNA and the mitochondria DNA are things that control the cell's everyday actions. 

Sometimes the malfunction in the mitochondria DNA is one of the reasons for some hereditary diseases. That means the mitochondria are underpowered or overpowered. So the cell cannot have strength if mitochondria are low power or it uses its nutrients too fast and boils the cell if mitochondria have overpowered. If mitochondrial metabolism is too high, the ion pumps in the cell cannot remove metabolic waste. And they cannot pump nutrients in. 

The reason for aging is in the DNA damage. Things like retroviruses transfer DNA from other species into human genomes. If that outcoming DNA will be at the point that controls the programmed cell death that can turn a cell into a cancer cell. 


https://scitechdaily.com/new-humanized-mice-brings-scientists-closer-to-reversing-aging/


 https://scitechdaily.com/the-secret-to-healthy-aging-scientists-uncover-the-power-of-selenoproteins/


Astronomers could have a model for why photons from GRB 221009A were at a high energy level.

"An illustration shows a photon from the biggest cosmic explosion since the Big Bang reaching Earth. (Image credit: Robert Lea (created...