Skip to main content

The phospholipid called diPUFA can used as a new type of cytostate.


"Illustration of a diPUFA phospholipid, a type of lipid with two polyunsaturated fatty acyl tails, breaking through a cell’s outer lipid layer as the cell dies. New research has shown that diPUFA phospholipids are a key driver of a form of cell death known as ferroptosis. Credit: Nicoletta Barolini/Columbia University" (ScitechDaily, Fatal Fats: Columbia Researchers Discover Rare Lipids Triggering Cell Death)

The new observations about lipids help to understand cell death. The lipid molecule. Or accurately saying phospholipid molecule called diPUFA can cause cell death called ferroptosis. The molecule will break itself through the cell's lipid layer. And then that thing causes cell death. 

The phospholipid is the molecule that can tunnel itself through the cell's shell, and that thing causes cell death. The diPUFA is a phospholipid, a type of lipid with two polyunsaturated fatty acyl tails. That molecule cuts the molecular bonds between cell lipids. And that thing causes cell death. 



Phospholipid arrangement in cell membranes. (Wikipedia, Phospholipid) 

As you see in image 2 the phospholipid has a hydrogen-phosphorus or hydrophilic head that makes this molecule tunnel itself through the cell membrane. Then that thing turns upside down, and then the tails turn to the mitochondria that will destroyed. 


"Phosphatidylcholine is the major component of lecithin. It is also a source for choline in the synthesis of acetylcholine in cholinergic neurons". (Wikipedia, Phospholipid)

An interesting thing about this chemical compound is that this lipide acts a little bit like nerve agents or nerve gases. In organophosphates the phosphorous causes tunneling through the skin. And that thing makes nerve gasses so deadly. The research of the lipid molecules. And especially phospholipids can also help to create protective systems and chemicals against nerve agents. 

But as you see. The phospholipids can be as deadly as ricin. The phospholipid can cause gangrenes in the human body. And those things cause death. The thing is that in the wrong hands, those phospholipids can be used as horrifying weapons. 

This diPUFA can used as the medicine that should destroy the cancer or bacteremia cells. The idea is that some carrier enzyme can transport diPUFA into the non-wanted cells. The diPUFA can be the next-generation cytostate. But that thing is also harmful. And all things there this type of molecule can use are not good. 


https://scitechdaily.com/fatal-fats-columbia-researchers-discover-rare-lipids-triggering-cell-death/

https://en.wikipedia.org/wiki/Ferroptosis

https://en.wikipedia.org/wiki/Phospholipid


https://learningmachines9.wordpress.com/2024/02/19/the-phospholipid-called-dipufa-can-used-as-a-new-type-of-cytostate/



Comments

Post a Comment

Popular posts from this blog

What is the difference between TR-3A and TR-3B? And are those planes real?

What is the difference between TR-3A and TR-3B? And are those planes real? Is TR-3B (0) "Black Triangle UFO" or is it only the piece of paper?  The study project, what is used to create advanced ideas for use of the nuclear-powered aircraft. Or is it the study project or black budget aircraft, where lost 2,3 trillion dollars (1)of the stealth bomber were gone. In this text is things, that might seem very difficult to accept, and when we are thinking about things like doubling the object or making it smaller by using huge layers of energy, nothing denies to test those things. But were those tests successful, there is no data about that in public Internet, so we must say that things like doubling the human or aircraft can be tested, but the results can be unknown.  But in the source two is the tale, what seems like impossible, those men, who got Noble Prize put at first time one atom to the box, and hit it with photon one photon in the box and hit it with th
Post a Comment
Read more

Mythic Planet X is an interesting thing because that allows the way to the perfect stealth technology.

  Mythic Planet X is an interesting thing because that allows the way to the perfect stealth technology.  Could a hypothetical Planet X tunnel all radiation?  The myth of Planet X still lives. Nobody ever saw that planet, and the thing that supports the theory of previously unknown large-size planets in Kuiper's belt are mysterious anomalies in Neptune's trajectory. The thing is that nothing else supports the theory of the existence of the "invisible planet". The size of the planet must be very big. And its gravitational field strong that it can affect Neptune's trajectory.  And the search for that mysterious planet is very long work. In some visions, the mysterious gravitational source is mentioned as the small black hole, but nobody understands why that black hole doesn't seem to interact.  In some other theories, Planet X is a glimpse of dark matter. And that thing makes it invisible. But there is one weakness. The dark matter object must have some kind of
Post a Comment
Read more

Nanoparticles are excellent tools for medicine transporters.

"Researchers have developed a new therapy for pancreatic cancer involving nanoparticles that stimulate immune responses and improve drug delivery. This innovative method has led to significant tumor reduction in mice and holds potential for treating other cancers. Credit: SciTechDaily.com" (ScitechDaily, New Nanoparticle Cancer Treatment Successfully Shrinks and Eliminates Pancreatic Tumors) Nanoparticles can carry medicines into wanted cells. The idea is that the same system that feeds those cells transports those nanoparticles into cells that need medicine. When a nanoparticle goes, into a cell, it releases the chemicals into the targeted cells. Because nanoparticles don't let medical molecules interact with a body that makes it possible to create new and more powerful cytostatics. Nanoparticles can transport things like ricin molecules into wanted cells.  Ricin is one of the most poisonous chemicals. That chemical is useful for next-generation cytostatics, if researche
Post a Comment
Read more